Skin Rejuvenation

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1. How can photo-rejuvenation improve aged skin?

2. How does Plasmalite ® work?

3. What are the conditions that Plasmalite could treat?

4. How many treatments are needed?

5. Who could be treated?

6. Are there any contraindications?

7. Are there any side effects?

8. How long does a typical session take?

9. What about skin color and different treatments?

10. What does the treatment involve?

11. Is there something the patient should be aware of?

12. What are the success criteria?

13. Is it effective in treatment of different scars?

1. How can photo-rejuvenation improve aged skin?

Sun damaged and/or aged skin is characterized not only by wrinkles, but also by epidermal and dermal atrophy, rough skin texture, irregular pigmentation “dyschromia”, telangiectasias, superficial pigmented lesions, laxity, enlarged pores and increased hair growth.

Attempts to treat damaged and/or aged skin have been made through a variety of methods including; dermabrasion, chemical peeling, injection of collagen and/or hyaluronic acid or injection of fat, as well as ablative CO2 and Erbium:YAG laser skin resurfacing. However, there is a fast growing interest in the development of non-invasive and non-ablative methods to treat aged or damaged skin.

A non-coherent broad band pulsed light source, Plasmalite, is the latest and most effective choice for  improvement of the overall skin appearance. The treatment improve lesions such as vascular and pigmented disorders, fine lines, enlarged pores, laxity of the skin as well as permanent hair reduction.

The basic principle of photo-rejuvenation and hair removal is the selective photo-thermolysis, i.e. selective heating of the unwanted skin lesions to various temperatures depending on the type of the lesion - without any damage to the surrounding skin.

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2. How does Plasmalite ® work?

Plasmalite uses filtered light to selectively target the melanin, haemoglobin and collagen by selective photo-thermolysis. A sapphire crystal wave-guide conducts the filtered light to the target chromophores in the tissues. The excessive potentially harmful heat that is generated in the epidermis is efficiently removed into the sapphire crystal due to its direct contact with the skin and high speed of heat removal (30 times compared to water or gel).

Clinical studies have shown that selective heating of the dermal collagen layer to a temperature of about 60°C stimulates the fibroblasts to produce new collagen. The increase in collagen production takes place during a period of 8-10 weeks and lasts for 6–12 months after the last treatment. The biological mechanism of photo-thermal collagen stimulation is not yet fully explained, but it is believed to be similar to the mechanism of wound healing after selective activation of the fibroblasts. A large number of clinical trials have proven that the method efficiently flattens wrinkles by increasing the thickness of the collagen layer.

Vascular lesions can be treated through selective absorption of the light by the haemoglobin at a wavelength band starting from selected  535 - 615 nm and from that cut on wavelength up to about 1000 nm. When the temperature reaches about 60-65°C the blood coagulates and the inner cells of the intermediate sized blood vessel denature causing the vessel to coagulate and collapse. In contrary to many short-pulsed laser, Plasmalite with its Long Pulsed Light does not cause purpura in the treated area. Purpra arises after rupture of the micro vessels due to rapid heating. This is a typical side effect experienced with short pulsed laser.

The broadband spectrum of Plasmalite generates a homogenous heating throughout the lesions, while the single wavelength lasers produce inhomogeneous heating, since the monochromatic light has a fixed absorption depth for a specific chromophore.

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3. What are the conditions that Plasmalite could treat?

Plasmalite ® has successfully been used for treatment of the following conditions: 

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Removal/bleaching of vascular lesions ( telangiectasia, hemangioma, spider veins, etc.).

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Removal/bleaching of hyper-pigmentations.

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Improvement of skin texture and fine lines through collagen stimulation and collagen shrinkage (non-invasive instant face lift).

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Improvement of of dyschromia resulting in an evenly coloured skin.

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Shrinkage of pores size.

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Permanent hair removal/ reduction.

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Improvement of acne, acne scarring,  scars and keloids.

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Treatment of dark circles around the eyes.

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Tattoo removal/bleaching.

Plasmalite ® machine can easily be adapted for each type of treatment by just choosing an appropriate combination of lamp and filter. Lamp and filter exchange is user friendly and takes only 1-2 minutes.

Note: Plasmalite ® has NOT been tested on any of the following conditions. Therefore, these conditions should not be considered for treatment.

-Over dark moles             - Psoriasis             -Diabetes            - Eczema or Dermatitis                 -Skin cancer               - Porphyria (Photo-sensitivity)

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4. How many treatments are needed?

The number of treatments required varies depending on the indication. Aged or sun-damage skin requires 2-5 subsequent treatments depending on the type of the lesion. Treatment schedule is typically an initial treatment followed by 2 - 4 treatment sessions each minimum 3 weeks apart. Tattoo, acne, scars, vascular and pigmented lesions normally requires between 1-6 treatments, depending on which affliction and its severity.

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5. Who could be treated?

Subjects with any skin type, either gender, any age, who have aged or sun damaged skin of grades I – IV and/or unwanted hair. Also vascular and pigmented lesions, acne and tattoos can be successfully treated.

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6. Are there any contraindications?

Subjects with disorders like active localized or systemic infections, compromised immune system, coagulation disorders and/or use of aspirin, cortisone, heparin, and elevated photosensitivity as well as pregnant patients should not be treated.

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7. Are there any side effects?

Most people experience moderate discomfort. In most cases there is no need for a topical anesthesia, but it could be used. Reddening and swelling of the skin are ordinary but harmless side effects that disappear in 15-30 hours. The skin can be felt tightened for 1-2 days. In extreme cases slight blistering may occur, which heals normally within a few days.

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8. How long does a typical session take?

The wave-guide covers an area of skin measuring approximately 10 mm x 20 mm. Each pulse occurs every 2-3 seconds. A full-face treatment takes less than 20-25 minutes.

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9. What about skin color and different treatments?

Most types of skin (Fitzpatrick type I - V) could be treated using different filters with different wavelength selection. Trials showed that people of Hispanic, Middle East or Pakistan/Indian origin usually need yellow-orange filters (cut on 565 or 580 nm), while Caucasians yellow filter (cut on 535 or 550 nm) for skin rejuvenation. A filter with cut on at 615 nm can be used for removal of brown to dark hair in all skin types.  Blond hair is difficult to treat but some individuals respond pretty well utilizing a filter with cut on wavelength of 580 nm. The various light spectrum shapes for different afflictions continues from the cut on wavelength up to about 1000 nm.

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10. What does the treatment involve?

When the client comes for a skin rejunevation (SR) treatment it is preferred to treat the whole face and not only some selected lesions, because the overall treatment provides a better result for all individual lesions. A trained therapist under supervision of a specialized doctor will discuss how Plasmalite works and evaluate if it is suitable for the client. A test patch will be performed to observe its effect on the client.

A thin layer of optical contact gel is spread over the area to be treated. The wave-guide is then applied over the area and a series of short light flashes are passed over each 10x20 mm spot. The patient does not often, but might not always see an immediate difference. However within 2-3 weeks after each treatment most subjects see a drastic improvement. Pigmented and vascular lesions as well as tattoos respond very fast to the treatment. That is also the case with “non invasive facelift” utilizing collagen shrinking as a result of selective heating. The impressive effect for collagen stimulation will be seen 2-3 months after last session.

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11. Is there something the patient should be aware of?

Some people are more sensitive to light than others. Therefore, it is important that the client is completely honest when filling out the assessment form. Test patching is necessary to check the clients suitability for treatment. Please note, however, that the test patch result will not necessarily be the same as the result after the completion of the treatment. The client should avoid exposure to the sun and sun beds for 4 weeks before and after treatment.

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12. What are the success criteria?

a) Overall cosmetic improvement as determined by the investigator (fair, good or excellent) at 3 months or last follow-up.

b) Overall cosmetic improvement as determined by the patient at 3 months or last follow-up.

c) Improvement of skin texture as expected/predicted by the investigator at 3 months or last follow-up.

d) Disappearance or bleaching of the vascular and /or pigmented lesions.

e) Permanent removal/reduction of the unwanted hair

f) Disappearance of acne and scarring.

h) Disappearance of tattoos.

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13. Is it effective in treatment of different scars?

Plasmalite is effectively used to improve the operation scars, stretch marks, tattoo, burnt scars and marks (see the photos).

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[Plasmalite ®] and [ProliteTm ] are trademarks of the product in Sweden & USA.
Tasnim Imp/Exp is the official distributor of the product in Egypt, Syria, Lebanon, Libya, Tunisia, Algeria and Morocco as well as some other countries in the Middle East.
Address: :Tasnim Imp/Exp., 64 Mohie Eldin Abd Elhameed, Naser City, Cairo, Egypt. Tel. [002022720735, 0020101481656].

Questions or problems regarding this web site should be directed to [tasnim0@lycos.com].
Copyright © 2002 [Tasnim Imp/Exp]. All rights reserved.
Last modified: Sunday October 06, 2002.